Evia Bio is a life science innovation company enabling the growing cell and gene therapy market

EviaBio is a life science innovation company enabling the growing cell and gene therapy market. We provide new non-DMSO cryopreservation solutions developed by a world-leading cryobiologist, Allison Hubel, PhD. We partner with early-stage researchers and cell and gene therapy companies involved in cell and gene therapies. Our solutions unlock the full potential of emerging life-saving therapies through the use of organic compounds to protect the integrity of cells during cryopreservation.

Virtually every cell & gene therapy relies on cryopreservation to preserve cells safely and efficiently for manufacturing and transport. These therapies need consistent and reproducible results with high cell viability for therapeutic effectiveness. Cell loss during cryopreservation and thaw may render the therapy ineffective.

The products are built on years of world-class cryobiological research completed by Allison Hubel, PhD, Founder and Chief Scientific Officer. “The products are combinations of molecules called osmolytes that work synergistically with cells and water at subzero temperatures,” explains Dr. Hubel. “Our technology protects a variety of cell types against the stresses of freeze-thaw, which is a necessary foundation to allow consistent results from initial testing through FDA approval”.
BlueCube Bio officially announced a company name transition to EviaBio, conconcurrent with the launch of a significant new cryopreservation technology for use in cell and gene therapies utilizing Induced Pluripotent Stem Cells (iPSCs).

Our Mission is  – Cell Preservation Powered by Nature

NATURE-INSPIRED, NONTOXIC PRESERVATION TO IMPROVE CELL MANUFACTURING, MAKING THE PROCESS:

  • Efficient – improve quality of preserved cells compared to standard methods
  • Safe – nontoxic preservatives are manufacturing-friendly and are safe to handle
  • Scalable – fit-for-purpose strategies enable batch manufacturing

BEYOND OUR PRESERVATIVE SOLUTIONS, WE OFFER:

  • Technical support for each product and protocol
  • R&D services to develop new, customized preservation technologies
  • End-to-end consultation to optimize your preservation workflow

FAQ

WHAT’S IN THE PRESERVATIVES?
The preservatives are DMSO-free and contain combinations of sugars, sugar alcohols, and amino acids in the optimal ratios to protect cells.
HOW DO I USE THE PRESERVATIVES?
Each preservative is designed for a specific cell type and comes with an optimized protocol.
CAN I USE A MR. FROSTY OR COOLCELL?
Yes, but passive freezing devices do not offer the same control as a controlled rate freezer. As a result, using these solutions with a passive freezing device will result in lower post thaw recovery and greater variability.
DO I HAVE TO INCUBATE THE CELLS IN THE PRESERVATIVE BEFORE USE?
Yes, the incubation time in the protocol is designed for optimal cryoprotective action of the preservatives on cells. Otherwise cell viability, recovery and/or function would be considerably lower.

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Room 2-434, Bench 33
Minneapolis, MN 55455
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